Generated by All in One SEO Pro v4.9.4.2, this is an llms.txt file, used by LLMs to index the site. # Moonwalk Biosciences Pioneering precision epigenetic medicines ## Sitemaps - [XML Sitemap](https://dev-moonwalk.pantheonsite.io/sitemap.xml): Contains all public & indexable URLs for this website. ## Pages - [Moonwalk Biosciences - #513850 / fa9b22 - Purple/Orange](https://dev-moonwalk.pantheonsite.io/) - By deeply profiling and targeting the epigenetic code, Moonwalk aims to reprogram cells to their healthy state, fundamentally enabling a new approach to how therapies are discovered and developed. - [Pipeline](https://dev-moonwalk.pantheonsite.io/pipeline/) - Pipeline Our Pipeline of multiple FIC targets addressing diverse adipose mechanisms and indications Indication Mechanism Discovery Target validation Preclinical candidate IND-enabling (DC) Clinical MW01 Indication: Obesity Mechanism: Lipolysis & lipid droplet regulation Stage: IND-enabling (DC) Q1 2027 NHP PD data MW02 Indication: Obesity Mechanism: Thermogenesis, brown & beige pathways Stage: Preclinical candidate MW03 Indication: Obesity - [Science](https://dev-moonwalk.pantheonsite.io/science/) - Science Moonwalk’s platform discovers and validates novel, causal targets in obesity Metabolic trait genetic analysis Epigenetic inter-sections Target validation Comprehensive metabolic trait genetic analysis Genes with human genetic support were identified through mapping genome-wide association study loci across a comprehensive panel of metabolic traits. Approaches used to map variants to genes include spatial proximity, colocalization - [Careers](https://dev-moonwalk.pantheonsite.io/careers/) - Walk with us Browse Open Roles Work with us Epigenome engineering is the next frontier of genetic medicines. Join us in this exciting new field that promises to create safer and more effective treatments for a broad range of diseases. About our name At Moonwalk we believe it's possible to move cellular states back toward - [Contact Us](https://dev-moonwalk.pantheonsite.io/contact/) - Contact Us Moonwalk has offices in San Diego and South San Francisco, CA Moonwalk Biosciences2 Tower Place, 8th FloorSouth San Francisco, CA 94080 We welcome partnering opportunities and look forward to hearing from you. Name Phone Email Message This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. Submit - [Privacy Statement (US)](https://dev-moonwalk.pantheonsite.io/privacy-statement-us/) - [Opt-out preferences](https://dev-moonwalk.pantheonsite.io/opt-out-preferences/) ## My Templates - [Pipeline item](https://dev-moonwalk.pantheonsite.io/?elementor_library=pipeline-item) - Pipeline item Indication: Mechanism: Stage: Discovery - [News Archive](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-archive-106) - Moonwalk in the news Publications News Stories Press Releases January 28, 2026 Epigenetic and genetic discovery of novel adipose tissue targets for obesity therapeutics (Keystone Symposium, Obesity Therapeutics 2026, Poster #2031) Read More November 11, 2025 ObesityWeek 2025 Read More September 24, 2025 Cell Fate Plasticity: From Reprogramming to Early Development (Presentation by Dr. Kathrin - [News Item](https://dev-moonwalk.pantheonsite.io/?elementor_library=news-item) - News Item Read More - [News Item](https://dev-moonwalk.pantheonsite.io/?elementor_library=news-item-2) - News Item - [Sitewide Header](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-header-57) - Content area - [Sitewide Footer](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-footer-74) - Content area - [home backup - Feb 2 2026](https://dev-moonwalk.pantheonsite.io/?elementor_library=home-backup-feb-2-2026) - Pioneering novel therapeutics in adipose biology and tissue, driven by deep genetic and epigenetic insights We are hiring passionate, talented moonwalkers. See our open roles. Walk with us Moonwalk's Team Leadership Board of Directors Team Alex Aravanis, MD, PhD Co-Founder, CEO Elaine Cheung, MS Chief Business Officer Arash Jamshidi, PhD Co-Founder, President & CTO John - [homepage backup May 2025](https://dev-moonwalk.pantheonsite.io/?elementor_library=homepage-backup-may-2025) - Pioneering novel therapeutics in adipose biology and tissue, driven by deep genetic and epigenetic insights We are hiring passionate, talented moonwalkers. See our open roles. Walk with us Our science By deeply profiling, elucidating, and targeting the epigenetic code, Moonwalk is discovering and developing therapies to return cells to their healthy state, fundamentally enabling a - [Team Bio Loop](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-single-post-601) - Moonwalk Team Team Bio Loop - [Default Kit](https://dev-moonwalk.pantheonsite.io/?elementor_library=default-kit) - [Press Release Single](https://dev-moonwalk.pantheonsite.io/?elementor_library=press-release-single) - Home | Press Release Single Press Release Single PrevValues Section – grey bg, img, horizontal News Type ArchiveNext - [OLD - Careers Open roles](https://dev-moonwalk.pantheonsite.io/?elementor_library=old-careers-open-roles) - Open Roles - [Team Member](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-loop-item-87) - Team Member - [Elementor Loop Item #396](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-loop-item) - Elementor Loop Item #396 Learn More - [Job Posting](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-single-post-318) - Job Posting Job Posting Name Phone Email Resume/CV Message Send This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. Name Phone Email Resume/CV Message Send This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. - [Press Release Archive](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-archive-2004) - Press Release Archives October 21, 2024 Moonwalk Biosciences to Present New Epigenetic Data at ObesityWeek® 2024 and The Liver Meeting® 2024 Read More August 19, 2024 Moonwalk Biosciences Appoints VP of Biology and Translational Science and Announces Formation of Cardiometabolic Advisory Board Read More April 22, 2024 Moonwalk Biosciences to Present Data Showcasing EpiRead™ and - [News Type Archive](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-archive-1960) - News Stories February 13, 2026 Exclusive: Feng Zhang’s epigenetic editing startup shifts focus to siRNA obesity therapies Read More May 2, 2024 ASGCT 2024: Moonwalk Biosciences Presents Multiplex Epigenetic Engineering Platform Read More January 4, 2024 Moonwalk Bio Grabs $57 Million, Joins Push for ‘Epigenetic’ Treatments Read More January 4, 2024 Feng Zhang, Grail founder - [Investor loop](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-loop-item-2) - [Press Release (no logo)](https://dev-moonwalk.pantheonsite.io/?elementor_library=press-release-no-logo) - Press Release (no logo) Read More - [Homepage with image lines](https://dev-moonwalk.pantheonsite.io/?elementor_library=homepage-with-image-lines) - Pioneering precision epigenetic medicines We are hiring passionate, talented moonwalkers. See our open roles. Walk with Us Our science By deeply profiling and targeting the epigenetic code, Moonwalk aims to reprogram cells to their healthy state, fundamentally enabling a new approach to how therapies are discovered and developed. First in the field Moonwalk is the - [Team Archive](https://dev-moonwalk.pantheonsite.io/?elementor_library=team-archive) - Moonwalk Team - [Values Section - grey bg, img, horizontal](https://dev-moonwalk.pantheonsite.io/?elementor_library=values-section-grey-bg-img-horizontal) - Our Values What we believe Join us and we will value you ... and expect you to: Come as you are​ Diversity is an overused word. True diversity is an under-appreciated goal that takes work every day. Bring yourself to work. It makes us all stronger. Respect the science -respect each other We launched a - [Careers - homepage](https://dev-moonwalk.pantheonsite.io/?elementor_library=careers-homepage) - Careers Walk with us as we develop effective, safe and durable epigenetic medicines that leverage the most comprehensive insights on cellular epigenetics to date across a variety of indications. View Open Roles - [Old epigenome](https://dev-moonwalk.pantheonsite.io/?elementor_library=old-epigenome) - Engineering the Epigenome Explore our News Advanced Predictive AI Moonwalk technology brings the most advanced AI prediction of Epigenetic targets, and the broadest set of epigenetic engineering tools. Complete epigenetic view Moonwalk’s novel platform technology provides a total view of the epigenome in both health and disease. - [Values Section (Careers)](https://dev-moonwalk.pantheonsite.io/?elementor_library=values-section-careers) - our values at moonwalk Open Roles Respect We value each other as individuals and as part of our long-standing team of scientists and business professionals. Urgency We are developing revolutionary treatments to help people who suffer from cardiovascular and neurological diseases. Stewardship We are entrusted with the science – revolutionizing epigenetic engineering – and with - [Elementor Error 404 #306](https://dev-moonwalk.pantheonsite.io/?elementor_library=elementor-error-404-306) - 404 Page not Found ## Pipeline Items - [MWₙ](https://dev-moonwalk.pantheonsite.io/pipeline-item/mwₙ/) - [MW09](https://dev-moonwalk.pantheonsite.io/pipeline-item/mw09/) - [MW08](https://dev-moonwalk.pantheonsite.io/pipeline-item/mw08/) - [MW05](https://dev-moonwalk.pantheonsite.io/pipeline-item/mw05/) - [MW03](https://dev-moonwalk.pantheonsite.io/pipeline-item/mw03/) - [MW02](https://dev-moonwalk.pantheonsite.io/pipeline-item/mw02/) - [MW01](https://dev-moonwalk.pantheonsite.io/pipeline-item/mw01/) ## News - [ObesityWeek 2025](https://dev-moonwalk.pantheonsite.io/news/obesityweek-2025/) - [Keystone Symposia: Obesity and Adipose Tissue](https://dev-moonwalk.pantheonsite.io/news/keystone-symposia-obesity-and-adipose-tissue/) - [Cell Fate Plasticity: From Reprogramming to Early Development (Presentation by Dr. Kathrin Plath, Cold Spring Harbor Laboratory Cell Fate Conversions 2025)](https://dev-moonwalk.pantheonsite.io/news/cell-fate-plasticity-from-reprogramming-to-early-development-presentation-by-dr-kathrin-plath-cold-spring-harbor-laboratory-cell-fate-conversions-2025/) - [Methylencoder: A Transformer Encoder Architecture Trained on Long-Read DNA Methylation Data Achieves Significant Performance Gains by Encoding Each of the 30M CpGs in the Genome and Incorporating Long-Range Fragment-Level Attention (Keystone Symposium: AI in Molecular Biology, Poster #1039)](https://dev-moonwalk.pantheonsite.io/news/methylencoder-a-transformer-encoder-architecture-trained-on-long-read-dna-methylation-data-achieves-significant-performance-gains-by-encoding-each-of-the-30m-cpgs-in-the-genome-and-incorporating-long/) - [Epigenetic and genetic discovery of novel adipose tissue targets for obesity therapeutics (Keystone Symposium, Obesity Therapeutics 2026, Poster #2031)](https://dev-moonwalk.pantheonsite.io/news/epigenetic-and-genetic-discovery-of-novel-adipose-tissue-targets-for-obesity-therapeutics-keystone-symposium-obesity-therapeutics-2026-poster-2031/) - [Exclusive: Feng Zhang’s epigenetic editing startup shifts focus to siRNA obesity therapies](https://dev-moonwalk.pantheonsite.io/news/exclusive-feng-zhangs-epigenetic-editing-startup-shifts-focus-to-sirna-obesity-therapies/) - [Moonwalk Biosciences to Present New Epigenetic Data at ObesityWeek® 2024 and The Liver Meeting® 2024](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-to-present-new-epigenetic-data-at-obesityweek-2024-and-the-liver-meeting-2024/) - SOUTH SAN FRANCISCO, CA – October 21, 2024 – Moonwalk Biosciences, a therapeutics company leveraging epigenetic biology and AI, will present new data using its epigenetic technology at two upcoming scientific conferences, The Liver Meeting® 2024, hosted by the American Association for the Study of Liver Diseases (AASLD), and ObesityWeek® 2024, organized by The Obesity - [Moonwalk Biosciences Appoints VP of Biology and Translational Science and Announces Formation of Cardiometabolic Advisory Board](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-appoints-vp-of-biology-and-translational-science-and-announces-formation-of-cardiometabolic-advisory-board/) - John Liles, Ph.D., joins Moonwalk’s leadership team as VP Biology and Translational Science to lead the discovery and early development of novel therapies for cardiometabolic diseases Advisory Board members bring world class expertise and insights to support and guide Moonwalk’s research programs SOUTH SAN FRANCISCO, Calif. & SAN DIEGO--(BUSINESS WIRE)-- Moonwalk Biosciences, an epigenetic biology - [Feng Zhang, Grail founder join forces on new gene editing startup, Moonwalk](https://dev-moonwalk.pantheonsite.io/news/feng-zhang-grail-founder-join-forces-on-new-gene-editing-startup-moonwalk/) - [Moonwalk Bio Grabs $57 Million, Joins Push for ‘Epigenetic’ Treatments](https://dev-moonwalk.pantheonsite.io/news/moonwalk-bio-grabs-57-million-joins-push-for-epigenetic-treatments/) - [ASGCT 2024: Moonwalk Biosciences Presents Multiplex Epigenetic Engineering Platform](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-raises-57m-to-edit-the-epigenome-2/) - [Moonwalk Biosciences to Present Data Showcasing EpiRead™ and EpiWrite™ Next-Generation Multiplex Epigenetic Engineering Platform at ASGCT 2024](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-to-present-data-showcasing-epiread-and-epiwrite-next-generation-multiplex-epigenetic-engineering-platform-at-asgct-2024/) - The EpiRead and EpiWrite platform will be presented for the first time highlighting high-resolution single-cell mapping of the methylome in conjunction with targeted methylation modifications. EpiWrite can perform seven simultaneous multiplexed edits of primary human cells at >85% efficiency for achieving all seven edits, a major breakthrough in genetic engineering. April 22, 2024 08:00 AM - [Moonwalk Biosciences Launches with $57 Million in Financing to Advance a New Class of Precision Epigenetic Medicines](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-launches-with-57-million-in-financing-to-advance-a-new-class-of-precision-epigenetic-medicines/) - Novel platform technology provides a complete view of the epigenome in health and disease, with the most advanced AI prediction of epigenetic targets, and the broadest set of epigenetic engineering tools. Co-founded by Alex Aravanis, M.D., Ph.D., former CTO of Illumina, world-renowned scientist Feng Zhang, Ph.D. of the Broad Institute of MIT and Harvard, and - [Moonwalk debuts with $57M and an epigenetic toolkit to reprogram disease](https://dev-moonwalk.pantheonsite.io/news/moonwalk-debuts-with-57m-and-an-epigenetic-toolkit-to-reprogram-disease/) - [Moonwalk steps out with $57m for epigenetic reprogramming platform](https://dev-moonwalk.pantheonsite.io/news/moonwalk-steps-out-with-57m-for-epigenetic-reprogramming-platform-2/) - [Moonwalk Biosciences Launches With $57M in Seed, Series A Financing](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-launches-with-57m-in-seed-series-a-financing/) - [Peninsula startup Moonwalk looks to rewire 'monster control switch' to change course of diseases](https://dev-moonwalk.pantheonsite.io/news/peninsula-startup-moonwalk-looks-to-rewire-monster-control-switch-to-change-course-of-diseases/) - [Backed by CRISPR pioneer Feng Zhang, epigenetics biotech Moonwalk debuts with $57M](https://dev-moonwalk.pantheonsite.io/news/backed-by-crispr-pioneer-feng-zhang-epigenetics-biotech-moonwalk-debuts-with-57m/) - [A new startup from Feng Zhang and an ex-Illumina executive zeroes in on the epigenome](https://dev-moonwalk.pantheonsite.io/news/a-new-startup-from-feng-zhang-and-an-ex-illumina-executive-zeroes-in-on-the-epigenome/) - [Moonwalk Biosciences Raises $57M to Edit the Epigenome](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-raises-57m-to-edit-the-epigenome/) - [Moonwalk Biosciences raises $57 million today to pursue epigenome engineering](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-raises-57-million-today-to-pursue-epigenome-engineering/) ## Indications - [Lipid lowering](https://dev-moonwalk.pantheonsite.io/indication/lipid-lowering/) - [Obesity](https://dev-moonwalk.pantheonsite.io/indication/obesity/) - [Obesity and other indications](https://dev-moonwalk.pantheonsite.io/indication/obesity-and-other-indications/) ## Mechanisms - [Additional targets and combinations in testing](https://dev-moonwalk.pantheonsite.io/mechanism/additional-targets-and-combinations-in-testing/) - [Adipogenesis and differentiation](https://dev-moonwalk.pantheonsite.io/mechanism/adipogenesis-and-differentiation/) - [Adipose endocrine function](https://dev-moonwalk.pantheonsite.io/mechanism/adipose-endocrine-function/) - [Energy homeostasis](https://dev-moonwalk.pantheonsite.io/mechanism/energy-homeostasis/) - [Lipolysis & lipid droplet regulation](https://dev-moonwalk.pantheonsite.io/mechanism/lipolysis-lipid-droplet-regulation/) - [Thermogenesis, brown & beige pathways](https://dev-moonwalk.pantheonsite.io/mechanism/thermogenesis-brown-beige-pathways/) ## Team Categories - [Leadership](https://dev-moonwalk.pantheonsite.io/team-category/leadership/) - [Team Member](https://dev-moonwalk.pantheonsite.io/team-category/team-member/) - [Board of Directors](https://dev-moonwalk.pantheonsite.io/team-category/board-of-directors/) ## News Types - [In the News](https://dev-moonwalk.pantheonsite.io/news-type/in-the-news/) - [Press Release](https://dev-moonwalk.pantheonsite.io/news-type/press-release/) - [Featured](https://dev-moonwalk.pantheonsite.io/news-type/featured/) - [Publications](https://dev-moonwalk.pantheonsite.io/news-type/publications/)