Generated by All in One SEO Pro v5.0.0.1, this is an llms.txt file, used by LLMs to index the site. # Moonwalk Biosciences Pioneering precision epigenetic medicines ## Sitemaps - [XML Sitemap](https://dev-moonwalk.pantheonsite.io/sitemap.xml): Contains all public & indexable URLs for this website. ## Pages - [Moonwalk Biosciences - #513850 / fa9b22 - Purple/Orange](https://dev-moonwalk.pantheonsite.io/) - By deeply profiling and targeting the epigenetic code, Moonwalk aims to reprogram cells to their healthy state, fundamentally enabling a new approach to how therapies are discovered and developed. - [Science](https://dev-moonwalk.pantheonsite.io/science/) - Science Moonwalk's AI-enabled discovery platform integrates large-scale human genetics, epigenomics and multi-omics with functional validation to identify and prioritize causal targets for cardiometabolic disease. Our platform combines:Human genetic studies across metabolic diseasesEpigenetic profiling of healthy and obese, subcutaneous and visceral, and white and brown adipose tissuesTissue-specific gene expression and other ‘omics analysesFunctional validation in primary - [Pipeline](https://dev-moonwalk.pantheonsite.io/pipeline/) - Pipeline A Pipeline of First-in-Class Adipose-Targeted Therapies Moonwalk is advancing a portfolio of adipose-targeted siRNA therapeutics across obesity and cardiometabolic diseases. Indication Mechanism Discovery Target validation Preclinical candidate IND-enabling (DC) Clinical MW01 Indication: Obesity Mechanism: Lipolysis & lipid droplet regulation Stage: IND-enabling (DC) Late 2027 MW08 Indication: Obesity Mechanism: Energy homeostasis Stage: Preclinical candidate MW05 - [Careers](https://dev-moonwalk.pantheonsite.io/careers/) - Walk with us Browse Open Roles Work with us Epigenome engineering is the next frontier of genetic medicines. Join us in this exciting new field that promises to create safer and more effective treatments for a broad range of diseases. - [Contact Us](https://dev-moonwalk.pantheonsite.io/contact/) - Contact Us Moonwalk has offices in San Diego and South San Francisco, CA Moonwalk Biosciences2 Tower Place, 8th FloorSouth San Francisco, CA 94080 We welcome partnering opportunities and look forward to hearing from you. Name Phone Email Message This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. Submit - [Privacy Statement (US)](https://dev-moonwalk.pantheonsite.io/privacy-statement-us/) - [Opt-out preferences](https://dev-moonwalk.pantheonsite.io/opt-out-preferences/) ## Team Members - [Eric Green, MD, PhD](https://dev-moonwalk.pantheonsite.io/team/eric-green/) - [Tamar Grossman, PhD](https://dev-moonwalk.pantheonsite.io/team/tamar-grossman/) - [Mike Varney, PhD](https://dev-moonwalk.pantheonsite.io/team/mike-varney/) - [Carel le Roux, PhD, FRCP](https://dev-moonwalk.pantheonsite.io/team/carel-le-roux/) - [Jeff Weng](https://dev-moonwalk.pantheonsite.io/team/jeff-weng/) - [Erle Holgersen](https://dev-moonwalk.pantheonsite.io/team/erle-holgersen/) - [Liyang Zhang, PhD](https://dev-moonwalk.pantheonsite.io/team/liyang-zhang-phd/) - [Gary Yeung, CFA](https://dev-moonwalk.pantheonsite.io/team/gary-yeung-cfa/) - [Matthew Shin, PhD](https://dev-moonwalk.pantheonsite.io/team/matthew-shin-phd/) - [Rigel Kishton, PhD](https://dev-moonwalk.pantheonsite.io/team/rigel-kishton-phd/) - [Feng Zhang, PhD](https://dev-moonwalk.pantheonsite.io/team/feng-zhang-phd/) - [Stephen Djedjos, M.D.](https://dev-moonwalk.pantheonsite.io/team/stephen-djedjos-m-d/) - [Brian Hubbard, PhD](https://dev-moonwalk.pantheonsite.io/team/brian-hubbard-phd/) - [Paul Cohen, MD, PhD](https://dev-moonwalk.pantheonsite.io/team/paul-cohen-md-phd-rockefeller-university/) - [Shingo Kajimura, PhD](https://dev-moonwalk.pantheonsite.io/team/shingo-kajimura-phd/) - [Paul Burton, MD](https://dev-moonwalk.pantheonsite.io/team/paul-burton/) - [Sara Fakhretaha Aval, PhD](https://dev-moonwalk.pantheonsite.io/team/sara-fakhretaha-aval/) - [Katie Wilson, PhD](https://dev-moonwalk.pantheonsite.io/team/katie-wilson/) - [Heike Blockus, PhD](https://dev-moonwalk.pantheonsite.io/team/heike-blockus-phd/) - [Tori Doran](https://dev-moonwalk.pantheonsite.io/team/tori-doran/) - [Chris Dimitropoulos](https://dev-moonwalk.pantheonsite.io/team/chris-dimitropoulos/) - [Arash Jamshidi, PhD](https://dev-moonwalk.pantheonsite.io/team/arash-jamshidi-phd/) - [Alex Aravanis, MD, PhD](https://dev-moonwalk.pantheonsite.io/team/alex-aravinas-md-phd/) - [Kaushik Thakkar, PhD](https://dev-moonwalk.pantheonsite.io/team/kaushik-thakkar-phd/) - [Elaine Cheung, MS](https://dev-moonwalk.pantheonsite.io/team/elaine-cheung-ms/) - [Justin Valley, PhD](https://dev-moonwalk.pantheonsite.io/team/justin-valley-phd/) - [John Liles, PhD](https://dev-moonwalk.pantheonsite.io/team/john-liles/) - [Larry Garrido](https://dev-moonwalk.pantheonsite.io/team/larry-garrido/) ## News - [ObesityWeek 2025](https://dev-moonwalk.pantheonsite.io/news/obesityweek-2025/) - [Keystone Symposia: Obesity and Adipose Tissue](https://dev-moonwalk.pantheonsite.io/news/keystone-symposia-obesity-and-adipose-tissue/) - [Cell Fate Plasticity: From Reprogramming to Early Development (Presentation by Dr. Kathrin Plath, Cold Spring Harbor Laboratory Cell Fate Conversions 2025)](https://dev-moonwalk.pantheonsite.io/news/cell-fate-plasticity-from-reprogramming-to-early-development-presentation-by-dr-kathrin-plath-cold-spring-harbor-laboratory-cell-fate-conversions-2025/) - [Methylencoder: A Transformer Encoder Architecture Trained on Long-Read DNA Methylation Data Achieves Significant Performance Gains by Encoding Each of the 30M CpGs in the Genome and Incorporating Long-Range Fragment-Level Attention (Keystone Symposium: AI in Molecular Biology, Poster #1039)](https://dev-moonwalk.pantheonsite.io/news/methylencoder-a-transformer-encoder-architecture-trained-on-long-read-dna-methylation-data-achieves-significant-performance-gains-by-encoding-each-of-the-30m-cpgs-in-the-genome-and-incorporating-long/) - [Epigenetic and genetic discovery of novel adipose tissue targets for obesity therapeutics (Keystone Symposium, Obesity Therapeutics 2026, Poster #2031)](https://dev-moonwalk.pantheonsite.io/news/epigenetic-and-genetic-discovery-of-novel-adipose-tissue-targets-for-obesity-therapeutics-keystone-symposium-obesity-therapeutics-2026-poster-2031/) - [Moonwalk Biosciences to Present New Epigenetic Data at ObesityWeek® 2024 and The Liver Meeting® 2024](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-to-present-new-epigenetic-data-at-obesityweek-2024-and-the-liver-meeting-2024/) - SOUTH SAN FRANCISCO, CA – October 21, 2024 – Moonwalk Biosciences, a therapeutics company leveraging epigenetic biology and AI, will present new data using its epigenetic technology at two upcoming scientific conferences, The Liver Meeting® 2024, hosted by the American Association for the Study of Liver Diseases (AASLD), and ObesityWeek® 2024, organized by The Obesity - [Moonwalk Biosciences Appoints VP of Biology and Translational Science and Announces Formation of Cardiometabolic Advisory Board](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-appoints-vp-of-biology-and-translational-science-and-announces-formation-of-cardiometabolic-advisory-board/) - John Liles, Ph.D., joins Moonwalk’s leadership team as VP Biology and Translational Science to lead the discovery and early development of novel therapies for cardiometabolic diseases Advisory Board members bring world class expertise and insights to support and guide Moonwalk’s research programs SOUTH SAN FRANCISCO, Calif. & SAN DIEGO--(BUSINESS WIRE)-- Moonwalk Biosciences, an epigenetic biology - [Moonwalk Biosciences Launches with $57 Million in Financing to Advance a New Class of Precision Epigenetic Medicines](https://dev-moonwalk.pantheonsite.io/news/moonwalk-biosciences-launches-with-57-million-in-financing-to-advance-a-new-class-of-precision-epigenetic-medicines/) - Novel platform technology provides a complete view of the epigenome in health and disease, with the most advanced AI prediction of epigenetic targets, and the broadest set of epigenetic engineering tools. Co-founded by Alex Aravanis, M.D., Ph.D., former CTO of Illumina, world-renowned scientist Feng Zhang, Ph.D. of the Broad Institute of MIT and Harvard, and ## News Types - [Press Release](https://dev-moonwalk.pantheonsite.io/news-type/press-release/) - [Featured](https://dev-moonwalk.pantheonsite.io/news-type/featured/) - [Publications](https://dev-moonwalk.pantheonsite.io/news-type/publications/)